Mind and Machine: Exploring Brain-Computer Interfaces

In neuroscience, the frontier of brain-computer interfaces (BCI) holds the promise of bridging the gap between the human brain and external devices, offering revolutionary applications in fields ranging from robotics and prosthetics to communication and beyond. In the lab, scientists studying and developing new BCI technology leverage the human brain’s electrical and physiological signals.

Electroencephalography (EEG), functional near-infrared spectroscopy (fNIRS), and steady-state visually evoked potentials (SSVEP) are among the primary physiological and psychophysiological signals utilized in these investigations. Multimodal integration of two or more signal types allows researchers and engineers to take advantage of multiple data streams in their applications and studies.

EEG, which can measure electrical activity in the brain, is a cornerstone of BCI research. Researchers can decode various mental states and intentions by analyzing EEG patterns, enabling users to control external devices through mere thought. fNIRS complements EEG by measuring changes in blood oxygenation levels, offering insights into brain function with superior spatial resolution. SSVEP, on the other hand, capitalizes on the brain’s response to visual stimuli, providing a means for precise control in BCI applications.

The practical implications of BCI research extend far beyond the laboratory setting. In robotics, BCIs facilitate direct brain-to-machine communication, empowering users to manipulate robotic arms or navigate autonomous vehicles with their thoughts alone. A study published in the Journal of Information Science Engineering explored ways that an SSVEP-based BCI could be used to control assembly line robots via a headset measuring the operator’s EEG signals. The signals would communicate instructions to robots while operators identified defective parts, which the robots would pick out. During the experiment, EEG signals were obtained using a B-Alert X24 headset. The EEG-based BCI produced a 93.33% success rate in correctly identifying and removing defective parts from the assembly line process, allowing the operator to effectively “collaborate with the robot and communicate defective parts without manually operating the robot.”

Prosthetics benefit immensely from BCI advancements, enabling seamless integration with the user’s neural signals for intuitive control and enhanced functionality. A 2023 study by a team of researchers from the University of California Irvine explored the viability of creating low-cost cortical stimulators for bi-directional BCI (BD-BCI) research. BD-BCI takes brain-computer-interfaces to the next level with the brain not only providing motor commands to an artificial limb but also allowing it to receive sensory input from such a device. A BIOPAC data acquisition and analysis system was used to validate the charge balancing of subcortical electrocorticographic (ECoG) implants used in a stimulator. The charge balancing test was performed on phantom tissue designed to simulate real brain tissue. The resulting study successfully demonstrated “clinical validation of a fully-programmable electrical stimulator, integrated into an embedded BCI system.”

As researchers continue to refine BCI technologies, the possibilities for real-world applications are boundless. BIOPAC is among the companies on the cutting edge of BCI research, partnering with other innovators to provide the latest in multimodal BCI technologies such as Axon-R. For additional information on Axon-R, check out our recent webinar on the device.


Are you planning to explore the frontiers of BCI in the lab? Our regional customer reps have all the knowledge you need to integrate BIOPAC products into your BCI study.

Helping Students Learn Biomedical Engineering

Students entering the rigorous Biomedical Engineering (BME) discipline learn a gamut of separate physiological signals to best study healthcare applications of new technology. Simply put, as new, advanced medical devices make their way into the market, biomedical engineers are on the front lines of discovering how to best utilize these devices and corresponding software to better serve in healthcare. Well-equipped and prepared biomedical engineers study a number of signals, movements, and physiological concepts in their research, including some of the following:

Data Acquisition & Analysis Systems Respiratory System & Pulmonary Function
Spectral Analysis & Histograms Bioimpedance (Cardiac Output & Blood Flow)
Amplifiers, Transducers, and Calibration Biomechanics—Angle, Acceleration, Distance, Velocity
ECG, EDA (GSR), EEG, EGG, EMG, and EOG Physiological Control Systems
Force, Pressure, Strain, Flow, Temperature, Sound, Light Chart, Overlap, Scope, and X/Y Displays
Brain Computer Interface Blood Pressure & Heart Sounds
Signal Analysis & Processing Compartmental Modeling
Filters (FIR & IIR) Gait Analysis
Instrumentation Design

Related scientific citations are available for BME research in nearly all these areas of interest, but for students and educators, simplified practical labs can lay the groundwork for more advanced BME areas of interest, such as Gait Analysis or Brain Computer Interface (BCI). Inherent in the design of BME education is the fusion between virtual software-based analysis and physical laboratory applications—a dichotomy that favors software-based learning and research more and more. Educating students in biomechanics, biomeasurement, and biomaterials is crucial to set them up for success in the BME field, whether they go into research, education, health services, or industry. Trained biomedical engineers utilizing virtual tools in lieu of a larger laboratory instrumentation setup can save upwards of $80,000 in hardware costs for their institution. Skills taught with virtual tools are better suited to the real world “new world” of software-based analysis and signal processing.

Physiological Signal Processing Labs—colloquially known as “breadboards”—are an excellent tool to further biomedical engineering education, through both basic lessons and the physical construction of the signal processing lab device, a foray into the physical engineering side of the BME vocations. Recorded signals are analyzed and processed via Biopac Student Lab Software—a leader in BME education for university laboratories and undergraduate studies.

For example, the Biopac Student Lab Breadboard Lab Set covers lessons on constructing and running the following signal processes:

  1. Square Wave Oscillator
  2. Instrumentation Amplifier
  3. Active Filter: High Pass
  4. Active Gain Block & Low Pass
  5. Notch Filter for 50/60 Hz Rejection
  6. QRS Detection: Band Pass Filter
  7. QRS Detection: Absolute Value Circuit
  8. QRS Detection: Low Pass Filter and Overall System Test

BIOPAC also offers Biomedical Engineering curriculum for EMG-controlled robotic labs, modeling, filtering, FFT, as well as a “Best Practices for Good Data” on-demand training series on fundamentals of physiological signal processing and support for an array of BME research applications.

The benefits of this approach to BME Education help “…viscerally engage the student in an inquiry-based learning environment.”¹  Upon construction of their own Signal Processing lab, students verify signal processing models against mathematical simulations and test the models against measured signals sourced on their own bodies.

BIOPAC offers a wide array of wired and wireless equipment that can be used in your research. To find more information on solutions for recording, teaching, and analyzing Biomedical Engineering data, you can visit our product category for BME on the BIOPAC website.

 

¹ Alan Macy, R&D Director, BIOPAC Systems, Inc.

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