Advancing technology allows researchers the ability to utilize physiological data in different forms. This includes utilizing mathematic models to answer research questions, making data openly accessible to those with similar research questions, and identify alternative approaches to physiological measurements. Studies recently published in the field of biomedical engineering provide examples of these different quantitative approaches.
Researchers Chalacheva et al. (2017) have identified vaso-occlusive crisis (VOC) as a complication unique to sickle cell disease, they wanted to identify if a lab induced VOC reaction was telling about the disease itself. Using heat pulses to evoke a VOC reaction, participants’ reaction were acquired through BIOPAC’s MP research system. Researchers were then able to create a math based model for the use in clinics, which could analyze the severity of sickle cell through measuring evoked VOC reactions.
Chest surface motion can provide insight in how the cardiovascular and respiratory systems act together, researchers Shafiq and Veluvolu (2107) attempted to model chest motion further. ECG, chest motion, and air flow were gathered through BIOPAC’s MP36R research system as participants were given a multitude of breathing tasks. The data acquired was used to create an algorithm to map out chest movements allowing for more precision with radiation therapy in treating lung cancer, which is often challenging and potentially dangerous. The dataset was made openly available, encouraging its use in chest motion modeling as well as other cardiovascular based research.
Blood pressure is an important indicator of various cardiovascular diseases, due to hypersensitive patient’s inability to use pressure cuffs; Shin and Min (2017) identified a need for an alternative form of BP acquisition. BIOPAC’s MP research system acquired the less invasive PPG measurements, the hypothesized as an alternative to blood pressure. The study identified PPG alone can’t be used to measure blood pressure, but allowed for the development of a pressure index for further research in alternative forms of blood pressure monitoring.
The above studies recognize the importance in analyzing trends and sharing data of physiological reactions. If interested in more articles regarding developments in biomedical engineering, visit BIOPACs research publication page. BIOPAC offers a variety of equipment for any research question, find more information on BME biomedical engineering solutions through visiting our applications page.